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. 2016 Feb 15;8(2):742–748.

Figure 1.

Figure 1

Proposed model of tumorigenesis due to loss or decreased BRD7 expression. Reduced BRD7 expression caused by gene mutations or epigenetic changes, c-Myc and miRNA, induced cell apoptosis, suppressed cell survival, proliferation, invasion and metastasis by ras/MEK/ERK pathway or other genes.