Figure 6.

Effect of polydatin on β-catenin mRNA and protein expression and TCF/LEF activity in human osteosarcoma cells. A and B. 143B osteosarcoma cells were treated with 0, 10, 30, and 100 μM polydatin, β-catenin mRNA and protein expression were determined at 48 h posttreatment. C. 143B cells were transfected with the β-catenin-TCF/LEF reporter pTOP-Luc for 24 h, and treated with the indicated concentrations of PD. Luciferase activity was determined at 48 h posttreatment. Each value is mean ± S.D. *P<0.05, **P<0.01.