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Silymarin had no effects on body weight and food intake. C57BL/6J mice (7 weeks) were fed with HFD for 20 weeks, and treated with vehicle (1% HPMC + 1% tween 20), INT-747 (30 mg/kg) or silymarin (30 mg/kg) for another 4 weeks (PO, QD). Lean mice were treated with vehicle only as a naïve control. Data were presented as Mean ± SEM. N=10.
