Figure 6.

Role of silymarin in lipid metabolism and oxidative stress in liver. At the termination of treatment, livers were removed and homogenated for real-time PCR analysis of mRNA expression. ACC1, acetyl-CoA carboxylase 1; CAT, catalase; CPT1A, carnitine palmitoyltransferase 1A; FAS, fatty acid synthase; MTP, mitochondrial trifunctional protein; PPARα, peroxisome proliferator-activated receptor-α; SOD1, superoxide dismutase 1; SREBP1c, sterol regulatory element binding protein 1c. Data were presented as Mean ± SEM. N=8. ###P < 0.001 vs. naïve group, ***P < 0.001 vs. vehicle group, **P < 0.01 vs. vehicle group, *P < 0.05 vs. vehicle group.