Table 5.
The contribution of 5-HTT gene by psychosocial variables to the odds ratio for MDD
| OR (95% CI) | p | ||
|---|---|---|---|
| Gender | F to M | 0.864 (0.487, 1.534) | 0.617 |
| Age | 1.017 (0.978, 1.058) | 0.391 | |
| 5-HTT LPR Genotypes | ls to ll | 1.036 (0.318, 3.375) | 0.953 |
| ss to ll | 1.274 (0.401, 4.041) | 0.681 | |
| 5-HTT VNTR Genotypes | STin2.12/10 | 0.575 (0.217, 1.524) | 0.266 |
| STin2.10/10 | n.a. | n.a. | |
| EPQ | 1.029* (1.011, 1.048) | 0.002 | |
| LES | 1.005 (0.998, 1.013) | 0.139 | |
| SSRS | 0.919* (0.876, 0.964) | 0.001 | |
| TCSQ | Positive | 0.858* (0.822, 0.896) | 0.000 |
| Negative | 1.103* (1.057, 1.151) | 0.000 | |
| LES x VNTR | LES x STin2.12/10 | 1.025* (1.001, 1.050) | 0.043 |
| LES x STin2.10/10 | n.a. | n.a. | |
*
p<0.05, considered statistically significant.