Table 4.
SNPs | Genotype | Number | Age, Years | Sex, Male/Female, n | ISS 1 | Sepsis, n | MOD 2 Score |
---|---|---|---|---|---|---|---|
rs135551 | AA | 5 | 40.8 ± 16.6 | 3/2 | 15.6 ± 3.8 | 2 | 4.0 ± 2.2 |
AG | 101 | 40.0 ± 11.7 | 87/14 | 21.3 ± 8.1 | 36 | 4.5 ± 2.2 | |
GG | 628 | 41.4 ± 12.1 | 501/127 | 22.5 ± 9.6 | 262 | 4.9 ± 2.6 | |
rs5769178 | AA | 525 | 40.9 ± 12.6 | 429/96 | 21.8 ± 9.3 | 209 | 4.8 ± 2.5 |
AC | 198 | 42.5 ± 10.6 | 156/42 | 23.3 ± 9.1 | 86 | 4.9 ± 2.6 | |
CC | 11 | 34.9 ± 7.6 | 6/5 | 28.9 ± 15.8 | 5 | 5.4 ± 2.7 | |
rs4253711 | AA | 21 | 40.1 ± 14.2 | 16/5 | 23.3 ± 12.9 | 7 | 4.5 ± 2.1 |
AG | 170 | 40.4 ± 11.5 | 132/38 | 22.3 ± 8.8 | 62 | 4.7 ± 2.5 | |
GG | 543 | 41.6 ± 12.2 | 443/100 | 22.3 ± 9.5 | 231 | 4.9 ± 2.5 | |
rs4823613 | AA | 436 | 41.5 ± 12.1 | 351/85 | 22.2 ± 9.6 | 186 | 5.0 ± 2.5 |
AG | 256 | 41.2 ± 12.0 | 207/49 | 22.4 ± 9.1 | 100 | 4.9 ± 2.5 | |
GG | 42 | 39.1 ± 12.9 | 33/9 | 22.8 ± 9.5 | 14 | 5.1 ± 2.6 | |
rs6902123 | CC | 2 | 41.2 ± 5.7 | 2/0 | 25.0 ± 4.2 | 1 | 5.5 ± 2.1 |
CT | 42 | 40.5 ± 12.0 | 31/11 | 21.1 ± 8.4 | 16 | 3.9 ± 1.8 | |
TT | 690 | 41.3 ± 12.1 | 558/132 | 22.4 ± 9.5 | 283 | 4.9 ± 2.5 | |
rs2016520 | CC | 69 | 41.7 ± 10.9 | 53/13 | 22.5 ± 8.9 | 25 | 4.6 ± 2.5 |
CT | 308 | 41.1 ± 12.0 | 243/65 | 22.3 ± 9.9 | 131 | 4.8 ± 2.4 | |
TT | 357 | 41.3 ± 12.4 | 292/65 | 22.2 ± 9.1 | 144 | 5.0 ± 2.6 | |
rs4684846 | AA | 147 | 41.0 ± 11.6 | 117/30 | 23.1 ± 9.1 | 63 | 5.3 ± 2.7 |
AG | 372 | 41.1 ± 12.4 | 302/70 | 22.0 ± 9.4 | 146 | 4.7 ± 2.3 | |
GG | 208 | 41.8 ± 11.9 | 166/42 | 22.2 ± 9.8 | 89 | 5.0 ± 2.7 | |
rs10865710 | CC | 316 | 41.0 ± 11.9 | 257/59 | 22.3 ± 10.0 | 116 | 4.9 ± 2.5 |
CG | 328 | 41.3 ± 12.3 | 263/65 | 22.3 ± 9.0 | 134 | 4.6 ± 2.3 | |
GG | 90 | 41.9 ± 12.0 | 71/19 | 22.4 ± 9.0 | 50 | 5.8 ± 3.0 | |
a1, b1 | a2 | ||||||
rs1822825 | AA | 149 | 41.9 ± 11.9 | 117/32 | 21.1 ± 9.3 | 60 | 4.9 ± 2.4 |
AG | 368 | 40.9 ± 12.2 | 299/69 | 22.6 ± 9.1 | 156 | 4.8 ± 2.6 | |
GG | 215 | 41.4 ± 12.1 | 174/41 | 22.6 ± 10.1 | 83 | 4.9 ± 2.4 |
1 Injury Severity Score; 2 multiple organ dysfunction; a1, p = 0.002; a2, p = 0.041 for the recessive model; b1, p = 0.046 for the dominant model.