Table 2.
Cost | Measures of infection | Measures of exposure | ||
---|---|---|---|---|
RDTa | Microscopya | PCRa | Serologyb | |
Cost per sample | $1.50 | $0.25 | $2.00 | $0.5 |
Detection limit | 100 to 200 p/μL | 4 to 100 p/μL | <4 p/μL (individual PCR); 100 p/μL (pooled PCR) | n/a |
Point-of-care test? | Yes | Yes, if basic laboratory services are available | No | n/a |
Capital equipment required | None | Microscope | PCR machine, pipettes, gel tanks. | Microplate reader |
Training and rigour | Minimal | Moderate | Very extensive | Extensive |
Turnaround time per sample | 15 minutes | 30 minutes | 2 days | 3 days |
Turnaround time for 1000 samples | n/a | Weeks | Typically a week for individual PCR and days for pooled PCR, however the turnaround time depends on staff costs and the type of PCR conducted. | Week |
Unpublished data.