TABLE 2.
Histologic and Immunohistochemical Comparison Between Noncutaneous Extranodal, Nodal, and PCFCL
| Extranodal N = 27 (%) |
Nodal N = 44 (%) |
PCFCL N = 8 (%) |
P | |
|---|---|---|---|---|
| Grade | ||||
| 1 | 17 (63) | 26 (59) | 4 (50) | NS |
| 2 | 6 (22) | 9 (20) | 1 (12) | |
| 3a | 4 (15) | 9 (20) | 3 (38) | |
| Growth pattern | ||||
| Follicular | 11 (41) | 33 (75) | 3 (38) | 0.004 |
| Follicular and diffuse | 2 (7) | 7 (16) | 3 (38) | |
| Focally follicular (diffuse) | 14 (52) | 4 (9) | 2 (24) | |
| Immunopositive cases* | ||||
| CD10 | 18 (67) | 39 (89) | 3 (38) | 0.014 |
| BCL2 | 24 (89) | 34 (77) | 3 (38) | NS |
| BCL6 | 25 (93) | 43 (98) | 8 (100) | NS |
| Ki-67 (median %) | 10 | 20 | 20 | NS |
| LMO2 | 27 (100) | 43 (98) | 8 (100) | NS |
| HGAL | 27 (100) | 43 (98) | 8 (100) | NS |
*
Cases scored as 1 and above were considered as immunopositive.
HGAL indicates human germinal center-associated lymphoma; PCFCL, primary cutaneous follicle center lymphoma.