Anti-synthetase antibodies |
30–40% |
Anti-Jo-1 |
anti-histidyl-tRNA synthetase |
most common (about 20% of idiopathic inflammatory myopathies) |
PL 12 |
anti-alanyl-tRNA synthetase |
PL 7 |
anti-threonyl-tRNA synthetase |
EJ |
anti-glycyl-tRNA synthetase |
OJ |
anti-isoleucyl-tRNA synthetase |
KS |
anti-asparaginyl-tRNA synthetase |
Zo |
anti-phenylalanyl-tRNA synthetase |
Ha |
anti-tyrosyl-tRNA synthetase |
Mi-2 (anti-nuclear ATPase/helicase) |
< 10% |
SRP signal recognition particle – anti-ribonucleoprotein (proteins 7SLRNA) |
5% |
Anti-TIF1-γ (anti-p155/140 autoantibodies) |
13–21% |
Anti-MDA-5 (cytoplasmic protein melanoma differentiation-associated gene 5 |
unknown |
NXP-2 (nuclear matrix protein) |
unknown |
Anti-SAE (anti-small ubiquitin-like modifier activating enzyme) |
5% |