Table I.
Clinical manifestations in our patients who exhibited anti-TIF1-γ positivity
| N | Gender | Age at disease onset | Diagnosis | Observation (months) | Cancer | Death | Smoking | Muscle symptoms | Skin lesions | Skeletal symptoms | Lung involvement | GI involve-ment | CK [U/l] | LDH [U/l] | AST [U/l] |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | F | 33 | NDCTD | 9 | no | no | no | mild | no | arthralgia | no | no | 65 | 170 | 27 |
| 2 | F | 51 | limited ocular myositis | 5 | no | no | no | localized | no | no | no | no | 34 | 122 | 19 |
| 3 | M | 55 | DM | 1 | stomach | no data | yes | no | swelling of the eyelids | no | no | no | 2337 | NP | 149 |
| 4 | F | 27 | no | 4 | no | no | no | mild | no | no | no | no | 1414 | 263 | 87 |
| 5 | F | 59 | PM | 102 | no | no | no | severe | no | severe | no | dysphagia | 25630 | 365 | 720 |
| 6 | F | 57 | DM | 18 | pulmonis | no | yes | severe | heliotrope rash, V-sign, erythematous and oedematous rashes on face, rashes on the trunk | no | no | no | 305 | 258 | 31 |
| 7 | M | 74 | rhabdomyolysis | 1 | no | no | yes | severe | no | no | no | no | 145924 | 4221 | 1767 |
| 8 | M | 84 | DM | 1 | no | yes | no | severe | erythematous rashes Gottron's signs V-sign, scarf-sign periungual erythema | no | fibrotic changes | dysphagia | 307 | 349 | 65 |
| 9 | F | 41 | DM | 9 | no | no | no | no | erythematous and oedematous rashes on face, rashes on the trunk; Raynaud | arthralgia | no | no | 101 | 328 | 46 |
| 10 | F | 53 | DM | 8 | ovarian | yes | no | severe | erythematous rashes on face, heliotrope rash, V-sign, scarf-sign; arm and leg oedema | no | no | dysphagia | 17288 | 871 | 504 |
| 11 | F | 62 | DM | 3 | colon | yes | no | severe | swelling of the eyelids, heliotrope rash, V-sign, scarf-sign | no | no | dysphagia | 1280 | 333 | 75 |
DM – dermatomyositis; NDCTD – undifferentiated connective tissue disease; NP – not performed