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Effects of PAM-2 on Motor Coordination of Mice
| PAM-2 (mg/kg IP) | % Impairment |
|---|---|
| 0 | 0.6 ± 0.6 |
| 8 | 0.0 ± 0.0 |
| 20 | 0.0 ± 0.0 |
The effect of PAM-2 on motor coordination was evaluated using the rotarod test in mice 15 min after injection of either PAM-2 or vehicle. Mice were placed on the rotarod for 3 min. Data were presented as mean ± SEM. % impairment of 5 to 6 animals for each group.
IP = intraperitoneal; PAM-2 = 3-furan-2-yl-N-p-tolyl-acrylamide.
