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. 2016 Apr 27;7:71. doi: 10.3389/fgene.2016.00071

Table 2.

Comparisons of BRCAPRO at age of diagnosis by patient's characteristics.

Variable Group n mean std p value
BRCA Negative 69 11.40 19.40 0.001
Positive 16 34.61 33.01
AJ ancestry No 77 15.7 25.08 0.078
Yes 7 18.4 12.84
Yes 18 19.60 29.84
First degree relatives with BC 0 47 9.17 18.55 0.0002
1 30 17.79 22.98
2 8 46.91 33.54
Second degree relatives with BC 0 6 3.97 3.27 0.815
1 37 15.92 22.3
2 20 21.49 31.77
Unknown 22 13.53 22.05
Total relatives with BC 0 9 5.07 6.81 0.0056
1 15 5.94 11.45
2 20 15.40 19.57
3 21 16.14 20.19
4 20 27.94 24.26
First degree relatives with ovarian cancer 0 80 16.09 24.57 0.982
1 5 10.62 16.65
Second degree relatives with ovarian cancer 1 6 32.42 39.57 0.511
2 2 50.30 63.78
Total relatives with ovarian cancer 0 68 12.60 20.60 0.103
≥1 17 28.44 32.70
BSO No 64 13.39 20.62 0.824
Yes 18 19.60 29.84
ER status Negative 11 16.83 26.78 0.005
Positive 59 12.73 21.56
PR status Negative 18 13.79 24.09 0.311
Positive 51 13.34 22.08
ER/PR ER negative-PR negative 11 16.83 26.78 0.098
ER positive-PR negative 7 9.03 20.16
ER positive-PR positive 51 13.34 22.08
Nuclear grade I 6 4.58 4.69 0.706
II 35 13.72 22.97
III 34 15.47 21.62