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. 2016 Apr 27;7:71. doi: 10.3389/fgene.2016.00071

Table 3.

Comparisons of BRCAPRO at 10 years later than age of diagnosis by patient's characteristics.

Variable Group n mean std p value
BRCA Negative 69 7.09 14.49 <0.0001
Positive 16 25.38 28.28
AJ ancestry No 77 10.66 19.9 0.099
Yes 7 10.41 8.54
First degree relative with BC 0 47 5.43 13.9 0.0002
1 30 12.64 19.31
2 8 32.59 28.47
Second degree relatives with BC 0 6 1.92 1.52 0.796
1 37 9.39 14.62
2 20 15.38 27.05
Unknown 22 10.40 19.58
Total relatives with BC 0 9 2.38 3.09 0.008
1 15 2.33 3.9
2 20 10.63 14.31
3 21 12.56 26.59
4 20 18.14 22.29
First degree relative with ovarian cancer 0 80 10.98 19.58 0.750
1 5 3.32 3.93
Second degree relatives with ovarian cancer 1 6 24.48 35.23 0.254
2 2 42.50 54.87
Total relatives with ovarian cancer 0 68 8.41 15.76 0.096
≥1 17 19.02 27.89
BSO No 64 8.08 15.44 0.553
Yes 18 14.93 23.3
ER status Negative 11 13.96 24.71 0.071
Positive 59 8.1 15.89
PR status Negative 18 10.79 20.98 0.354
Positive 51 8.50 16.43
ER/PR ER negative-PR negative 11 13.96 24.71 0.151
ER positive-PR negative 7 5.81 13.49
ER positive-PR positive 51 8.50 16.43
Nuclear grade I 6 2.57 2.73 0.594
II 35 8.3 17.1
III 34 10.69 15.86