Table 4.
Comparisons of BRCAPRO with DCIS entered as no cancer by patient's characteristics.
| Variable | Group | n | mean | std | p value |
|---|---|---|---|---|---|
| BRCA | Negative | 69 | 1.98 | 6.09 | 0.003 |
| Positive | 16 | 2.56 | 2.63 | ||
| AJ ancestry | No | 77 | 2.18 | 5.87 | 0.192 |
| Yes | 7 | 1.34 | 1.16 | ||
| First degree relative with BC | 0 | 47 | 0.61 | 1.28 | <0.0001 |
| 1 | 30 | 2.00 | 2.94 | ||
| 2 | 8 | 11.05 | 14.93 | ||
| Second degree relatives with BC | 0 | 6 | 0.20 | 0.20 | 0.429 |
| 1 | 37 | 1.73 | 2.92 | ||
| 2 | 20 | 2.95 | 7.63 | ||
| Unknown | 22 | 2.40 | 7.48 | ||
| Total relatives with BC | 0 | 9 | 0.20 | 0.21 | 0.0025 |
| 1 | 15 | 0.52 | 1.19 | ||
| 2 | 20 | 1.43 | 2.69 | ||
| 3 | 21 | 3.17 | 7.90 | ||
| First degree relative with ovarian cancer | 0 | 80 | 2.15 | 5.76 | 0.527 |
| 1 | 5 | 1.12 | 1.38 | ||
| Second degree relatives with ovarian cancer | 1 | 6 | 2.68 | 3.85 | 0.366 |
| 2 | 2 | 3.10 | 1.84 | ||
| Total relatives with ovarian cancer | 0 | 68 | 2.05 | 6.10 | 0.062 |
| ≥1 | 17 | 2.23 | 2.91 | ||
| Bilateral salpingo-oophorectomy (BSO) | No | 64 | 1.75 | 4.78 | 0.287 |
| Yes | 18 | 1.56 | 2.30 | ||
| ER status | Negative | 11 | 0.96 | 1.83 | 0.527 |
| Positive | 59 | 2.29 | 6.49 | ||
| PR status | Negative | 18 | 1.06 | 2.21 | 0.330 |
| Positive | 51 | 2.46 | 6.90 | ||
| ER/PR | ER negative-PR negative | 11 | 0.96 | 1.83 | 0.604 |
| ER positive-PR negative | 7 | 1.20 | 2.87 | ||
| ER positive-PR positive | 51 | 2.46 | 6.90 | ||
| Nuclear grade | I | 6 | 0.48 | 0.49 | 0.679 |
| II | 35 | 1.93 | 6.09 | ||
| III | 34 | 2.61 | 6.24 |