Table 2. IC50 values and the drug resistance reversion index (RRI) of various formulations of PTX against MCF-7/ADR cells.
Formulations | IC50 values (μg mL–1) | RRI a |
Free PTX | 14.9 | — |
Free PTX + curcumin | 9.4 | 1.6 |
PTX@PEG–PCDA | 7.1 | 2.1 |
PTX@BPP | 1.68 | 8.9 |
PTX/MNPs/QDs@BPP | 1.70 | 8.7 |
PTX/MNPs/QDs@BPP | ||
Plus magnetic field | 0.89 | 16.7 |
aResistance reversion index (RRI): the ratio of IC50 for free paclitaxel to that of paclitaxel with reversal agents against the MCF-7/ADR cells.