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. Author manuscript; available in PMC: 2017 Feb 18.
Published in final edited form as: Cell Chem Biol. 2016 Feb 18;23(2):214–224. doi: 10.1016/j.chembiol.2016.01.004

Figure 7. Synthetic molecules and natural products that target agr.

Figure 7

(A) Global AgrC inhibitors derived from native AIPs. Groups that differ from the wild-type AIP are highlighted in red. (B) AIP-mimicking natural products. (C) The Pseudomonas autoinducers 3-oxo-C12-HSL and HQNO. (D) The AgrA-targeting lead compound, savarin.