Table 4.

Cox proportional hazard modeling of predictors for heart failure and cardiac death among soft tissue sarcoma (STS) patients in Western Denmark (regional cohort, N=539), 1997–2011

Predictor	Heart failure	Cardiac death	Overall mortality
	Hazard ratio (95% confidence interval)	Hazard ratio (95% confidence interval)	Hazard ratio (95% confidence interval)
Age, per year increase	1.00 (0.94–1.05)	1.1 (1.02–1.18)	1.03 (1.02–1.04)
Male (reference: female)	1.52 (0.35–6.5)	2.93 (0.57–15.04)	0.94 (0.72–1.22)
Received doxorubicin treatment*	2.18 (0.46–10.23)	–	4.92 (3.67–6.59)
Year of diagnosis, per year increase	1.02 (0.82–1.28)	0.88 (0.70–1.11)	0.98 (0.94–1.02)
Leiomyosarcoma**	0.93 (0.18–4.77)	1.21 (0.19–7.83)	0.67 (0.50–0.92)
Liposarcoma**	0.66 (0.11–4.17)	1.25 (0.19–8.05)	0.51 (0.35–0.72)
Pre-existing cardiovascular disease*	6.31 (0.98–40.55)	5.86 (0.82–42.06)	1.14 (0.85–1.50)

Notes:

^*Reference group is none.

^**Reference group is all other STS subtypes.

Abbreviation: –, not available.