Table 2.

Mitochondrial proteins involved in metabolic processes that show altered expression levels in transgenic ELC mice

Protein name	UniProt	Gene	PANTHER protein class	A57G versus WT (FC)	Δ43 versus WT (FC)	Δ43 versus A57G (FC)
Aldehyde dehydrogenase, mitochondrial	P47738	ALDH2_MOUSE	Dehydrogenase	1.20*	−1.21*	−1.46*
Atpase inhibitor, mitochondrial	O35143	E9PV44_MOUSE	–	−1.58*	−1.20	1.32
Citrate lyase subunit beta-like protein, mitochondrial	Q8R4N0	CLYBL_MOUSE	–	1.07	−1.03	−1.11*
Cytochrome C oxidase subunit 5B, mitochondrial	P19536	COX5B_MOUSE	Oxidase	−1.12	1.04	1.12*
Cytochrome B-C1 complex subunit 7	Q9CQB4	Q9CQB4_MOUSE	–	−1.07	1.07	1.15*
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial	Q8CHT0	AL4A1_MOUSE	Dehydrogenase	−1.14*	−1.42*	−1.25*
Isovaleryl-COA dehydrogenase, mitochondrial	Q9JHI5	IVD_MOUSE	Dehydrogenase	1.10	1.00	−1.11*
Cluster of inorganic pyrophosphatase 2, mitochondrial	D3Z636	D3Z636_MOUSE	–	1.19*	−1.03	−1.25*
FUMARATE hydratase, mitochondrial	P97807	FUMH_MOUSE	Lyase	1.14*	1.03	−1.09
3-Ketoacyl-COA thiolase, mitochondrial	Q8BWT1	THIM_MOUSE	Acetyltransferase	1.14	1.16*	−1.03
Mitochondrial 2-oxoglutarate/malate carrier protein	Q9CR62	M2OM_MOUSE	Calmodulin	1.28*	1.00	−1.29*
NAD(P) Transhydrogenase, mitochondrial	Q61941	NNTM_MOUSE	Dehydrogenase	1.13*	−1.29	−1.46*
NADH dehydrogenase [ubiquinone] 1 alpha Subcomplex subunit 9, mitochondrial	Q9DC69	NDUA9_MOUSE	Dehydrogenase	1.13*	1.00	−1.13
NADH dehydrogenase [ubiquinone] iron-sulphur protein 4, mitochondrial	E9QPX3	E9QPX3_MOUSE	–	−1.07	1.13	1.19*
succinyl-COA ligase [GDP-forming] subunit beta, mitochondrial	Q9Z2I8	SUCB2_MOUSE	Ligase	1.20*	1.07	−1.14*
Short-chain specific acyl-COA dehydrogenase, mitochondrial	Q07417	ACADS_MOUSE	Dehydrogenase	1.13	1.00	−1.15*
Trifunctional enzyme subunit alpha, mitochondrial	Q8BMS1	ECHA_MOUSE	Dehydrogenase, hydratase, epimerase	1.10	1.13*	1.03

^*P < 0.05. FC fold change. Negative FC values indicate proteins that were downregulated, while positive FC values those which were upregulated