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. Author manuscript; available in PMC: 2016 Jul 6.
Published in final edited form as: Adv Synth Catal. 2015 Jul 14;357(10):2233–2237. doi: 10.1002/adsc.201500313

Table 5.

Asymmetric hydroacylation of ketones using [Rh(L14)]BF4.

graphic file with name nihms735238u5.jpg
Entry Keto Amide Product Time [h] Yield [%] ee [%]
1 graphic file with name nihms735238t6.jpg
2f 		graphic file with name nihms735238t7.jpg
3df 		18 86 40
2 graphic file with name nihms735238t8.jpg
2i 		graphic file with name nihms735238t9.jpg
3di 		18 87 40
3 graphic file with name nihms735238t10.jpg
2c 		graphic file with name nihms735238t11.jpg
3dc 		45 36 60
a

Conditions: 1d (2 equiv), 2 (1 equiv), [Rh(nbd)2]BF4 (0.1 equiv), L14 (0.1 equiv), DCE, 30 °C.