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. 2016 Apr 27;11(4):e0153919. doi: 10.1371/journal.pone.0153919

Fig 1. Effect of CD40L and rosuvastatin on the expression of P4Hα1 and gelatinases in HASMCs.

Fig 1

(A, B and E) MMP2, P4Hα1 and collagen expression after treated with 0, 2, 5, and 10 μg/ml rhsCD40L for 8 h by qRT-PCR (A), western blot analysis (B) and gelatin zymography (E). (C, D and F) MMP2 and P4Hα1 expression after treated with 5 μg/ml rhsCD40L for 0, 4, 8 and 12 h by qRT-PCR (C), western blot analysis (D) and gelatin zymography (F). (G and H) P4Hα1 and collagen expression after treated with or without rhsCD40L and rousuvastatin by qRT-PCR (G) and western blot analysis (H). *P < 0.05 vs. control, #P <0.05 vs. CD40L.