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. 2016 Apr 27;12(4):e1004877. doi: 10.1371/journal.pcbi.1004877

Fig 4. A flow diagram of a MEDYAN simulation.

Fig 4

(1) After the chemical stochastic simulation evolves the network in time and (2) local deformations are formed, (3) a mechanical equilibration is performed and (4) reaction rates are updated according to chosen functional forms f(F current) where F current is the force on that reacting molecule after equilibration.