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. 2015 Sep 6;7(3):404–412. doi: 10.1111/jdi.12408

Table 3.

Relationship between either of the elasticity or cross‐sectional area of the tibial nerve and clinical factors, severity of diabetic neuropathy, cross‐sectional area of the tibial nerve or neurophysiological tests in type 2 diabetic patients

Elasticity of tibial nerve CSA of tibial nerve
Standardized β P Standardized β P
Sex 0.044 0.555 −0.188 0.018
Age −0.163 0.035 0.112 0.134
Body mass index −0.028 0.729 0.064 0.404
Duration of diabetes mellitus −0.044 0.552 0.061 0.393
Diastolic blood pressure −0.021 0.788 0.015 0.873
HbA1c −0.100 0.193 0.034 0.646
Low‐density lipoprotein cholesterol 0.010 0.894 −0.097 0.192
High‐density lipoprotein cholesterol −0.041 0.618 −0.009 0.905
Triglycerides −0.025 0.753 0.133 0.085
Severity of diabetic neuropathy −0.596 <0.0001 0.306 <0.0001
Cross‐sectional area of tibial nerve −0.234 0.002
Motor nerve conduction velocity of median nerve 0.296 <0.0001 −0.360 <0.0001
Amplitude of median nerve 0.046 0.551 −0.076 0.311
Sensory nerve conduction velocity of ulnar nerve 0.324 <0.0001 −0.200 0.006
Amplitude of ulnar nerve 0.123 0.110 −0.102 0.168
Vibration perception threshold −0.067 0.391 0.058 0.437
Current perception threshold 2000 Hz −0.191 0.011 0.147 0.043
Current perception threshold 250 Hz −0.107 0.144 0.113 0.111
Current perception threshold 5 Hz −0.081 0.264 0.090 0.200
Coefficient of variation in R‐R interval 0.136 0.080 −0.029 0.698

HbA1c, glycated hemoglobin.

Multivariate regression analysis was used to determine the independent relationship between either of the elasticity or cross‐sectional area (CSA) of the tibial nerve and clinical factors, stages of diabetic neuropathy, cross‐sectional area of the tibial nerve, or neurophysiological examinations.