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. 2016 Apr 27;11(4):e0154425. doi: 10.1371/journal.pone.0154425

Table 1. Association Rules for the Adverse Drug Reactions Reported for SSRI, SNRI, and NaSSA.

Type X Y Support Confidence Lift Conviction
SSRI Aspartate aminotransferase increased Alanine aminotransferase increased 0.0059 0.93 135.5 13.9
Alanine aminotransferase increased Alanine aminotransferase increased 0.0059 0.87 135.5 7.5
Gamma-glutamyl transferase increased, Aspartate aminotransferase increased Alanine aminotransferase increased 0.0032 1.00 145.9 NA
Gamma-glutamyltransferase increased, Aspartate aminotransferase increased Aspartate aminotransferase increased 0.0032 0.88 136.8 7.9
Blood lactate dehydrogenase increased Alanine aminotransferase increased 0.0021 0.82 119.4 5.5
SNRI International normalised ratio increased Drug interaction 0.0064 1.00 71.9 NA
Irritability Anxiety 0.0064 0.86 114.5 6.9
Anxiety Irritability 0.0064 0.86 114.5 6.9
Aspartate aminotransferase increased Alanine aminotransferase increased 0.0032 1.00 233.8 NA
Cardio-respiratory arrest Pulmonary oedema 0.0032 1.00 311.7 NA
NaSSA Anxiety Irritability 0.0058 0.80 49.9 4.9
Multi-organ failure Agranulocytosis 0.0044 1.00 98.0 NA
Confusional state Hallucination, visual 0.0029 1.00 57.2 NA
Hypothyroidism Myopathy 0.0029 1.00 228.7 NA
Cerebellar ataxia Altered state of consciousness 0.0029 1.00 52.8 NA