. Author manuscript; available in PMC: 2016 Apr 27.

Published in final edited form as: Eur Radiol. 2015 Apr 30;26(1):15–24. doi: 10.1007/s00330-015-3796-y

Table 3.

Characteristics of participants based on thymic score

	Thymic Score				P Value^{†, ‡}
	0 (N=1869)	1 (N=463)	2 (N=172)	3 (N=36)	P Value^{†, ‡}

Age — year	61.7 ± 11.7	51.2 ± 8.6	50.8 ± 8.4	47.0 ± 7.6	<0.001

Female sex — no. (%)	888 (48)	261 (56)	116 (67)	31 (86)	<0.001

Body-mass index (kg/m²)^*	29.3 ± 5.5 (N=1856)	26.7 ± 4.6 (N=462)	25.3 ± 4.1	23.8 ± 3.5	<0.001

Smoking status —no. (%)
Never	823 (44)	275 (60)	108 (63)	23 (64)	<0.001
Former	912 (49)	154 (33)	55 (32)	10 (28)	<0.001
Current	117 (6) (N=1852)	31 (7) (N=460)	8 (5) (N=171)	3 (8)	0.8

Pack-year	20.3 ± 18.7 (N=965)	12.8 ± 14.1 (N=174)	11.1 ± 11.6 (N=60)	6.8 ± 12.2 (N=10)	0.04

Plus-minus values are mean ± standard deviation.

Percentages may not add to 100 due to rounding.

The body-mass index (BMI) is calculated with the following equation: $BMI = \frac{body weight (kg)}{height {(m)}^{2}}$

^†

P values were calculated with the use of linear mixed effect models or generalized estimating equations to account for familial relationships in the Framingham Heart Study, as described previously [16].

^‡

P values for BMI, smoking status, and pack-year were the results of analyses adjusted for age and sex. In addition, P values for BMI and pack-year were also adjusted for pack-year and BMI, respectively.