Table 4.
Genes differentially expressed after knocked down of PP2Ac treatment in hepatoma 3B Cells (n = 3 )
| Refseq | Symbol | Description | Fold change of shPP2A-A1/Control shRNA |
|---|---|---|---|
| Up-regulated | |||
| NM_000389 | CDKN1A | Cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 30.06 ± 2.354 |
| NM_003392 | WNT5A | Wingless-type MMTV integration site family, member 5A | 16.99 ± 1.427 |
| NM_004064 | CDKN1B | Cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 15.73 ± 1.257 |
| NM_014417 | BBC3 | BCL2 binding component 3 | 10.23 ± 0.942 |
| NM_000903 | NQO1 | NAD(P)H dehydrogenase, quinone 1 | 6.59 ± 0.576 |
| NM_006516 | SLC2A1 | Solute carrier family 2 (facilitated glucose transporter), member 1 | 6.01 ± 0.533 |
| NM_000321 | RB1 | Retinoblastoma 1 | 5.89 ± 0.474 |
| NM_000043 | FAS | Fas (TNF receptor superfamily, member 6) | 5.65 ± 0.529 |
| NM_004185 | WNT2B | Wingless-type MMTV integration site family, member 2B | 5.46 ± 0.438 |
| Down-regulated | |||
| NM_033131 | WNT3A | Wingless-type MMTV integration site family, member 3A | 0.077 ± 0.019 |
| NM_017617 | NOTCH1 | Notch 1 | 0.135 ± 0.031 |
| NM_005438 | FOSL1 | FOS-like antigen 1 | 0.141 ± 0.027 |
| NM_053056 | CCND1 | Cyclin D1 | 0.146 ± 0.029 |
| NM_005228 | EGFR | Epidermal growth factor receptor | 0.189 ± 0.034 |
| NM_002467 | MYC | V-myc myelocytomatosis viral oncogene homolog (avian) | 0.196 ± 0.039 |
| NM_000201 | ICAM1 | Intercellular adhesion molecule 1 | 0.196 ± 0.048 |
| NM_003376 | VEGFA | Vascular endothelial growth factor A | 0.197 ± 0.057 |