Table 2.
Cancer related genes within regions of differential gains and losses in epithelioid malignant mesothelioma (MM), by tumor site.
| Pleural |
Peritoneal |
|||
|---|---|---|---|---|
| Gain | Loss | Gain | Loss | |
| Chr1 | TNFRSF14 | TRIM33 | ||
| DVL1 | UBE4B | |||
| Chr2 | ||||
| Chr3 | PBRM1, SETD2 | RAF1 | PIK3CA | |
| Chr4 | KIT | |||
| Chr5 | ACSL6 | |||
| Chr6 | CCND3, TFEB | |||
| Chr7 | MLL3 | EGFR, ELN | ||
| HIP1 | ||||
| Chr8 | RECQL4 | WRN | RUNX1T1 | |
| MYC | ||||
| Chr9 | CDKN2A | NOTCH1 | ||
| RALGDS | ||||
| Chr10 | BMPR1A | KLF6 | ||
| SUFU | FGFR2 | |||
| Chr11 | CCND1 | |||
| Chr12 | KDM5A | PTPN11 | KRAS | |
| HOXC11 | ||||
| HOXC13 | ||||
| Chr13 | FLT3 | |||
| Chr14 | ||||
| Chr15 | CASC5 | |||
| Chr16 | FUS | |||
| HERPUD1 | ||||
| Chr17 | RABEP1 | BRCA1, RARA | ||
| SUZ12 | CANT1 | |||
| Chr18 | ||||
| Chr19 | STK11, ELL, AKT2 | |||
| Chr20 | ASXL1 | |||
| Chr21 | ||||
| Chr22 | PDGFB, MKL1, SMARCB1 | |||
| EP300, CHEK2, NF2 | ||||
| PATZ1, MYH9 | ||||
| CLTCL1, BCR | ||||