Table 3.

Univariate and multivariate analyses for overall survival.

		Univariate analysis			Multivariate analysis
Variables		HR	95% CI	P-value	HR	95% CI	P-value
Age	< 65	1	reference	–	1	reference	–
	≥ 65	0.777	0.482-1.251	0.299	1.824	0.628-15.299	0.269
Smoking status	None	1	reference	–	1	reference	–
	Current and ex-smoker	3.151	1.087-9.135	0.035	11.47	2.510-52.404	0.002
EGFR subtypes	Simple	1	reference	–	1	reference	–
	Compound	2.489	0.925-6.695	0.071	4.030	1.305-12.446	0.015
Stage	IB	1	reference	–	1	reference	–
	IIA-IIB	1.717	0.211-13.988	0.614	3.985	0.313-50.713	0.287
	IIIA	2.300	0.287-18.41	0.433	9.078	0.743-110.883	0.084
Histologic subtypes	Acinar	1	reference	–	1	reference	–
	Papillary and micropapillary	1.229	0.387-3.898	0.726	0.590	0.175-1.985	0.394
	Lepidic	1.575	0.357-6.943	0.548	0.890	0.161-4.928	0.894
	Solid	0.256	0.012-5.344	0.380	0	–	0.981
	Others	0.591	0.028-12.390	0.735	0	–	0.988