Table 7.
Type of EGFR mutation | Average of co-mutations in other genes | |
---|---|---|
Simple mutation | E19del (n = 24) | 0.7 |
V738_K739insKIPVAI (n = 1) | 0 | |
M766_A767insASV (n = 1) | 0 | |
D770_N771insG+N771T (n = 1) | 1 | |
N771F (n = 1) | 0 | |
L858R (n = 17) | 0.5 | |
L861R (n = 1) | 0 | |
Compound mutation | L858R + V689L (n = 1) | 1 |
L858R + L833V (n = 1) | 0 | |
L858R + H870R (n = 1) | 0 | |
L858R + A871G (n = 1) | 10 | |
L858R+ R776H (n = 1) | 19 | |
L858R + E19del (n = 1) | 0 | |
G719A + I706T (n = 1) | 0 | |
G719S + E709K (n = 1) | 0 | |
G719S + R776H (n = 1) | 0 | |
E19del + I706T (n = 1) | 0 | |
D770_N771insNPY + H773Y (n = 2) | 1 | |
L688F + G824S (n = 1) | 34 | |
E749Q + A750P (n = 1) | 0 | |
T785I + Y813H + V845M + V851I + G857R (n = 1) | 19 |