Table 2. Participant demographics based on existence of pulmonary cysts.
| No pulmonary cysts (N= 2433) |
Pulmonary cysts (N=200) |
P Value*1,2 | |
|---|---|---|---|
|
| |||
| Age — year | 58.9 ± 12.0 (range 34.0, 92.0) | 63.0 ± 12.0 (range 40.1, 89.8) | <0.001 |
|
| |||
| Female sex — no. (%) | 1229 (51) | 96 (49) | 0.5 |
|
| |||
| Body-mass index*3 | 28.6 ± 5.4 (N=2420) |
27.1 ± 4.7 | <0.001 |
|
| |||
| Smoking status —no. (%) | |||
| Never | 1188 (49) | 80 (40) | 0.1 |
| Former | 1088 (45) | 108 (54) | 0.2 |
| Current | 150 (6) (N=2426) |
12 (6) | 0.7 |
|
| |||
| Pack-years | 17.9 ± 18.1 (N=1238) |
19.8 ± 17.6 (N=120) |
0.9 |
|
| |||
| Coronary artery calcium score*4 | 190.2 ± 530.9 (N=2303) |
167.9 ± 344.7 (N=188) |
0.006 |
|
| |||
| Respiratory symptoms — no. (%) | |||
|
| |||
| Chronic cough | 168 (7) | 8 (4) | 0.8 |
|
| |||
| Shortness of breath with minor exertion | 273 (11) | 18 (9) | 0.051 |
Plus-minus values are mean ± standard deviation.
*1
P values were calculated with the use of mixed effect models or generalized estimation equations to account for familial relationships in the Framingham Heart Study, as described previously [15].
*2
P values for BMI, smoking status, pack-years, coronary artery calcium score and respiratory symptoms were adjusted for age and sex. In addition, the result for coronary artery calcium score was adjusted for the presence of emphysema; the results for respiratory symptoms were adjusted for smoking status and pack-years.
*3
The body-mass index is the weight in kilograms divided by square of the height in meters.
*4
Coronary artery calcium scores were calculated by the Agatston method [27].