TABLE 1. An Overview of Manual and Automated IMT Measurement Studies for the Left and Right CCA in Normal and Cardiovascular Disease Groups.
Study | Year | Method | N | Left CCA mean(std) (mm) | Right CCA mean(std) (mm) | p-value | |||
---|---|---|---|---|---|---|---|---|---|
Manual | Auto | Manual | Auto | Manual | Auto | ||||
Normal Group | |||||||||
Bots [11] | 1997 | Manual | 1500 | 0.79(0.21) | - | 0.78(0.22) | - | 0.65 | - |
Schmidt [15] | 1998 | Manual/automated | 50 | 0.88(0.25) | 0.85(0.19) | 0.86(0.24) | 0.84(0.20) | 0.43 | 0.49 |
Willekes [12] | 1999 | Manual/Ultramark | 16 | 0.52(0.46) | 0.49(0.45) | 0.55 (0.42) | 0.51(0.64) | 0.55 | 0.83 |
Sun [8] | 2002 | Manual B-mode | 1781 | 0.68(0.12) | - | 0.66(0.12) | - | 0.0004 | - |
Rodriquez [7] | 2003 | Manual B-mode | 102 | 0.75(0.11) | - | 0.71(0.11) | - | 0.001 | - |
Arbel [6] | 2007 | -/M’ATH | 98 | - | 0.625(0.078) | - | 0.626(0.075) | - | 0.884 |
Luo [9] | 2011 | QIMT | 447 | 0.49(0.09) | - | 0.47(0.09) | - | - | 0.002 |
This study | 2014 | Manual/automated | 976 | 0.74(0.20) | 0.73(0.20) | 0.70(0.17) | 0.69(0.19) | 0.56 | 0.77 |
CVD Group | |||||||||
Bots [11] | 1997 | Manual | 60 | 1.23(1.03) | - | 1.29(1.08) | - | 0.42 | - |
Willekes [12] | 1999 | Manual/Ultramark | 13 | 0.74(0.74) | 0.71(0.46) | 0.73(0.61) | 0.73(0.69) | 0.67 | 0.03 |
Vicenzini [30] | 2007 | Manual | 1655 | - | 0.97(0.21) | - | 0.95(0.19) | - | 0.001 |
Lee [10] | 2011 | Manual | 149 | 0.83(0.24) | - | 0.83(0.21) | - | 0.72 | - |
This study | 2014 | Manual/automated | 125 | 0.87(0.24) | 0.86(0.23) | 0.80(0.18) | 0.81 (0.18) | 0.02 | 0.04 |
CVD: Cardiovascular events; N: Number of cases investigated; significantly (shown underlined) and non-significantly different at and respectively.