. Author manuscript; available in PMC: 2016 Oct 11.

Published in final edited form as: Nat Genet. 2016 Apr 11;48(5):544–551. doi: 10.1038/ng.3548

Table 1.

Unexplained drug resistance in 498 strains of M. tuberculosis from South Africa and China. The total number of strains assayed for phenotypic resistance to each drug is shown, along with the number of phenotypically resistant (R) and phenotypically susceptible (S) strains. The number of strains with phenotypic drug resistance but without a match to known resistance-associated mutations is also given.

	# of phenotyped strains			# strains w/unexplained R
Drug	Total	R	S	# strains w/unexplained R
Rifampicin	498	337	161	8
Isoniazid	498	350	148	21
Pyrazinamide	142	72	70	12
Ethambutol	394	164	230	15
Streptomycin	498	256	242	21
Ofloxacin	494	162	332	15
Kanamycin	491	104	387	20
Capreomycin	300	66	234	15
Ethionamide	288	102	186	16