Table 1.
%Bias, coverage and relative efficiency for estimated treatment effect on cost
| normal | lognormal | gamma | mixed | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| light censoring | %bias | Coverage | MSER | %bias | Coverage | MSER | %bias | Coverage | MSER | %bias | Coverage | MSER |
| naive regression | −40.56 | 0.09 | 125.14 | −34.32 | 0.04 | 42.32 | −30.23 | 0.04 | 4.15 | −34.31 | 0.05 | 29.36 |
| covariates adjustmt: normal | 0.11 | 0.94 | 2.34 | −12.81 | 0.52 | 12.65 | −7.86 | 0.84 | 0.83 | −14.15 | 0.41 | 5.79 |
| covariates adjustmt: lognormal | 1.82 | 0.36 | 3.66 | −1.48 | 0.95 | 2.80 | 18.74 | 0.74 | 2.43 | −15.67 | 0.17 | 6.43 |
| covariates adjustmt: gamma | 0.35 | 0.95 | 2.36 | 2.62 | 0.94 | 1.19 | 0.35 | 0.96 | 0.62 | −11.45 | 0.49 | 3.90 |
| stratification | −1.43 | 0.84 | 10.33 | −8.99 | 0.85 | 5.84 | −3.30 | 0.90 | 1.15 | −4.73 | 0.89 | 3.23 |
| IPTW | −0.81 | 0.99 | 49.38 | −2.72 | 0.90 | 8.18 | −0.74 | 0.92 | 1.74 | −0.38 | 0.95 | 6.80 |
| IPTW: normalized | 0.13 | 0.94 | 39.94 | −0.03 | 0.90 | 7.26 | −0.09 | 0.90 | 1.61 | −0.08 | 0.93 | 5.75 |
| DR: normal | 0.02 | 0.97 | 1.00 | 0.83 | 0.92 | 1.85 | −0.36 | 0.91 | 1.00 | 0.44 | 0.95 | 1.34 |
| DR: lognormal | −0.02 | 0.96 | 1.08 | 0.36 | 0.94 | 1.01 | −0.42 | 0.92 | 1.04 | 0.03 | 0.97 | 1.03 |
| DR: gamma | −0.02 | 0.96 | 1.07 | 0.91 | 0.94 | 1.00 | −0.36 | 0.92 | 1.00 | 0.04 | 0.94 | 1.00 |
| DR: SL in regression model | 0.01 | 0.97 | 1 (ref) | 0.96 | 0.96 | 1 (ref) | 0.07 | 0.94 | 1 (ref) | 0.01 | 0.93 | 1 (ref) |
| moderate censoring | ||||||||||||
| naive regression | −67.59 | 0.04 | 188.13 | −25.61 | 0.03 | 35.21 | −44.57 | 0.02 | 5.59 | −47.69 | 0.08 | 32.93 |
| covariates adjustmt: normal | 0.56 | 0.92 | 2.92 | −12.18 | 0.69 | 7.10 | −8.12 | 0.87 | 0.76 | −14.69 | 0.48 | 4.14 |
| covariates adjustmt: lognormal | 2.33 | 0.52 | 4.14 | −1.49 | 0.97 | 4.47 | 33.36 | 0.59 | 3.76 | −13.47 | 0.51 | 3.43 |
| covariates adjustmt: gamma | 0.78 | 0.94 | 2.95 | 2.55 | 0.93 | 1.07 | 0.52 | 0.96 | 0.59 | −11.78 | 0.60 | 2.86 |
| stratification | −24.97 | 0.85 | 54.56 | −2.66 | 0.92 | 7.05 | −12.30 | 0.82 | 1.80 | −14.08 | 0.78 | 6.05 |
| IPTW | −1.68 | 0.90 | 92.04 | 2.14 | 0.96 | 10.49 | −6.58 | 0.90 | 2.36 | −5.51 | 0.90 | 8.49 |
| IPTW: normalized | 0.73 | 0.90 | 86.74 | 2.10 | 0.95 | 10.08 | −1.27 | 0.89 | 2.24 | −1.33 | 0.88 | 8.14 |
| DR: normal | −0.70 | 0.92 | 1.00 | 1.93 | 0.94 | 1.82 | −1.32 | 0.95 | 1.01 | −1.90 | 0.94 | 1.30 |
| DR: lognormal | −0.82 | 0.94 | 1.08 | 2.01 | 0.95 | 1.00 | −2.17 | 0.95 | 1.04 | −1.86 | 0.94 | 1.03 |
| DR: gamma | −0.79 | 0.94 | 1.08 | 2.01 | 0.95 | 0.98 | −1.15 | 0.96 | 1.01 | −1.72 | 0.94 | 1.00 |
| DR: SL in regression model | −0.73 | 0.96 | 1 (ref) | 1.81 | 0.97 | 1 (ref) | −1.12 | 0.97 | 1 (ref) | −1.41 | 0.95 | 1 (ref) |