Table 1.
miRNA | Targets | Regulation | [Ref] |
---|---|---|---|
let-7 | EZH2, Lin28B, c-MYC, RAS, HMGA2, CDC25a, CDC34, CDK6 | Cell proliferation, EMT, stem cell renewal | 47, 65 – 67 |
miR-200 | ZEB1, ZEB2, TGF-β | EMT, stem cell renewal | 66, 68, 69 |
miR-34a | AR, E2F3, NOTCH1, DLL1, NANOG, SOX2 | AR signaling, stem cell renewal | 51, 65, 68, 70 |
miR-124 | AR, CDK6, ITGB1, FOXA2 | AR signaling, cell proliferation | 66, 71 |
mi-27b | AR, LIMK1, VEGF, Rac1 | AR signaling, angiogenesis | 72 – 74 |
miR-320 | β-Catenin, RUNX2, MIB1 | Stem cell renewal | 54, 75 |