Table 1.
Study Subjects
| COPD Gene NHW | COPD Gene AA | ECLIPSE | GenKOLS | NETT | |
|---|---|---|---|---|---|
| N | 2792 | 811 | 1757 | 853 | 364 |
| Population origin | US | US | Europe/US/New Zealand | Norway | US |
| Age | 64.7 (8.2) | 59.0 (8.2) | 63.7 (7.1) | 65.6 (10.0) | 67.5 (5.8) |
| Males (%) | 55.6 | 54.7 | 66.9 | 60.0 | 64.8 |
| Pack-years | 56.2 (27.8) | 42.4 (23.1) | 50.3 (27.4) | 32.1 (18.5) | 66.1 (30.9) |
| Current smoker (%) | 34.7 | 60.8 | 35.4 | 46.9 | 0 |
| BMI (kg/m2) | 28.1 (6.1) | 28.0 (6.8) | 26.7 (5.6) | 25.3 (4.9) | 25.0 (3.5) |
| FEV1 pp (%) | 49.7 (18.0) | 52.3 (17.7) | 47.6 (15.6) | 50.7 (17.3) | 28.0 (7.4) |
| FEV1/FVC | 0.49 (0.13) | 0.53 (0.12) | 0.45 (0.12) | 0.51 (0.13) | 0.32 (0.06) |
| BDRABS (L) | 0.10 (0.15) | 0.07 (0.18) | 0.12 (0.14) | 0.10 (0.14) | 0.09 (0.08) |
| BDRBASE (%) | 9.2 (12.4) | 7.6 (14.2) | 10.7 (13.4) | 8.1 (11.7) | 13.4 (12.0) |
| BDRPRED (%) | 3.6 (4.9) | 2.89 (6.5) | 3.9 (4.8) | 3.4 (4.7) | 3.3 (3.0) |
Data are presented as mean (sd) or N (%). NHW: non-Hispanic white; AA: African American; FEV1pp: FEV1 percent predicted; BMI: Body mass index. BDRABS: (Post-BD FEV1 – Pre-BD FEV1); BDRBASE: (BDRABS/(Pre-BD FEV1*100)); BDRPRED: (BDRABS/(FEV1pp*100)).