Fig. 2.

a, b Kaplan-Meier curves for graft survival in relation to donor and recipient heme oxygenase-1 guanine-thymine dinucleotide repeat gene polymorphism. The heme oxygenase-1 genotype is composed of a combination of short ≤25 alleles, and/or long (>25 repeats) alleles with the genotypes short-short, short-long, and long-long. According to donors’ heme oxygenase-1 genotypes, graft survival rates of donor livers with the short-long genotype are comparable to that of the short-short homozygotes (log rank p = 0.81), and significantly higher than the donor livers with long-long genotype (log rank p = 0.015). However, graft survival rates did not differ significantly according to the recipients’ heme oxygenase-1 genotypes (log rank p = 0.93). SS short-short, SL short-long, LL long-long. c, d Kaplan-Meier curves for graft survival in relation to donor and recipient heme oxygenase-1 guanine-thymine dinucleotide repeat gene polymorphism. The heme oxygenase-1 genotype was stratified in patients and donors as carriers vs. noncarriers of short allele. According to donors’ heme oxygenase-1 genotypes, the survival of short-allele grafts were significantly longer than grafts of long homozygotes (log rank p = 0.017). However, graft survival rates did not differ significantly according to the recipients’ heme oxygenase-1 genotypes (log rank p = 0.229). S short, L long