Table 1.

Description of prospective cohort studies

Study	Country	Study type	Patient (n)	Aim	QOL instruments	Follow-up
Zieren et al. [31]	Germany	Prospective	106	Long-term follow-up after gastrectomy	EORTC QLQ-C36 Spitzer index	12 months
Wu et al. [12]	Taiwan	Prospective, RCT	214	D1 versus D3 lymphadenectomy	Spitzer index	Baseline, 6, 12, 24, 36, 48 and 60 months
Avery et al. [32]	UK	Prospective	58	QOL in patients that died within 2 years versus survivors	EORTC QLQ-C30 EORTC QLQ-STO22	Baseline, 3,6,9, and 12, 18 and 24 months
Svedlund et al. [17]	Sweden	Prospective, RCT	64	Total or subtotal gastrectomy, with or without pouch reconstruction	GSRS SIP	Baseline, 3,12, 24, 36, 48 and 60 months
Karanicolas et al. [33]	USA	Prospective	134	Total, distal or proximal gastrectomy	EORTC QLQ-C30 EORTC QLQ-STO22	Baseline, 3, 6, 9, 12, 18 months
Munene et al. [21]	Canada	Prospective	43	Partial versus total gastrectomy	FACT-G FACT-GA	Baseline, every 3 months in 2 years
Kim et al. [34]	Korea	Prospective	465	Total versus subtotal gastrectomy	EORTC QLQ-C30 EORTC QLQ-STO22	Baseline, 3 and 12 months
Takiguchi et al. [29]	Japan	Prospective, RCT	268	Roux-en Y versus Billroth I reconstruction	EORTC QLQ-C30 DAUGS20	21 months (range 3 - 34)
Kono et al. [18]	Japan	Prospective, RCT	47	Roux-en Y versus pouch reconstruction	GSRS	3, 12, 48 months
Horvath et al. [16]	Hungary	Prospective, RCT	46	Roux-en Y versus pouch reconstruction	GIQLI	6, 12 and 24 months
Scurtu et al. [25]	Romania	Prospective	39	Total gastrectomy with E–E versus E–S anastomosis	Korenaga score	3 and 12 months
Kim et al. [35]	Korea	Prospective, RCT	164	Open versus laparoscopy-assisted distal gastrectomy	EORTC QLQ-C30 EORTC QLQ-STO22	Baseline, 1, 3, 6 and 12 months