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. 2016 Apr 20;90(2):308–319. doi: 10.1016/j.neuron.2016.03.015

Figure 6.

Figure 6

Glycinergic Control of “Sustained” Signals through the ON Pathway

(A) Density of contrast-activated ON terminals across the whole IPL, before and after injection of strychnine and Gabazine. Gabazine injection significantly increased the number of ON terminals generating a significant response at any frequency, while strychnine injection decreased it (∗∗p < 0.01; ∗p < 0.05). Collected results from 632 ON terminals in 7 fish.

(B) Response amplitude as a function of frequency averaged from contrast-activated ON terminals before (green, n = 114) and after Gabazine (black, n = 120) or strychnine (blue, n = 28). Note that Gabazine increased peak gain, while strychnine reduced the response amplitudes at low frequencies.

(C) Density of contrast-suppressed ON terminals, before and after injection of strychnine and Gabazine. Strychnine significantly increased the number of contrast-suppressed terminals.

(D) Response amplitude as a function of frequency averaged from contrast-suppressed ON terminals before (green, n = 146) and after Gabazine (black, n = 57) or strychnine (blue, n = 164).