Figure 4.

Effects of metformin and sitagliptin on glycolipid metabolism after high lipid diet. Rats in metformin groups were gavaged by 200 mg/kg metformin or 10 mg/kg sitagliptin before being gavaged by 45% glucose (4.5 ml/kg, HCD group), 20% lipid emulsion (4.5 ml/kg, HLD group), 20% lactalbumin (10 ml/kg, HPD group) or mixed diet (1 : 1 : 1 of above diet ingredients, MD group). The energy was 33 kJ for all the diets

HCD – high carbohydrate diet, HLD – high lipid diet, HPD – high protein diet, MD – mixed diet; *compared with control group p < 0.05; #compared with metformin group p < 0.05.