Table III.

Sensitivity and specificity of calculated values of selected biochemical and hematological parameters in differentiation between bacterial and aseptic meningitis

Parameter	Sensitivity (%)	95% CI	Specificity (%)	95% CI	+LR	–LR
CRP > 84 mg/l	98.46	91.7–99.7	100	94.3–100		0.02
D-dimers > 970 µg/l	90.77	81.0–96.5	89.19	74.6–96.9	8.40	0.10
Fibrinogen > 4.4 g/l	95.38	87.1–99.0	80.43	66.1–90.6	4.88	0.06
Glucose > 95 mg/dl	64.62	51.8–76.1	79.69	67.8–88.7	3.18	0.44
WBC > 13/µl	71.43	58.7–82.1	82.81	71.3–91.1	4.16	0.35
Glucose CSF ≤ 40 mg/dl	66.15	53.4–77.4	93.75	84.7–98.2	10.58	0.36
Leukocytes CSF > 992	76.92	64.8–86.5	90.62	80.7–96.5	8.21	0.25
Protein CSF > 0.96 g/l	83.08	71.7–91.2	90.62	80.7–96.5	8.86	0.19
Age ≤ 74 months	64.62	51.8–76.1	79.69	67.8–88.7	3.18	0.44
BMS > 1	93.85	85.0–98.3	93.75	84.7–98.2	15.02	0.07

The first percentage for each marker corresponds to the marker's sensitivity. Values are the 95% CIs for sensitivity. The second percentage for each marker corresponds to the marker's specificity. Values are the 95% CIs for specificity. BMS – Bacterial Meningitis Score, CRP – C-reactive protein, CSF – cerebrospinal fluid, CI – confidence intrerval, +LR – positive likelihood ratio, – LR – negative likelihood ratio, WBC – white blood cells.