Table II.

Cardioprotective agents used in AIC

Drug	Actions	References
Dexrazoxane	Antioxidant agent against development of AIC, without increasing non-cardiac and non-hematologic toxicity	[75]
Selenium	Antioxidant agent	[78]
Probucol	Antioxidant agent preserves cardiac function	[83]
Ranolazine	Selective inhibitor of the cardiomyocyte late inward sodium current (INaL), with anti-ischemic, antiarrhythmic and ATP-sparing actions	[85]
Statins	Inhibition of the Ras-homologous GTPase Rac1	[86]
β-blockers	Antioxidant and anti-apoptotic effects	[88]