Table 3.

Characteristics of Propensity Score Matched Subgroups for Planned Sensitivity Analysis

	Alvimopan				p Value
	No		Yes
	n	%	n	%
Patient characteristic	834	50.0	834	50.0
Median age, y (range)	60 (18–97)		62 (18–96)		0.07*
Female	467	56	474	57	0.73†
Private insurance	435	52	433	52	0.75
Charlson Score‡					0.74
0	611	73	618	74
1	179	22	176	21
2	34	4	27	3
3	10	1	13	2
ASA Class
1	48	5.8	58	7	0.618
2	507	60.8	489	58.6
3	271	32.5	276	33.1
4	8	1	11	1.3
BMI 18.5–25 kg/m2	291	35	284	34	0.95
Home oxygen	2	<1	6	1	0.16
Mobility device§	15	2	13	2	0.70
Current smoker	138	17	142	17	0.79
Operative characteristic
Laparoscopic‖	432	52	397	48	0.09
Median operating time, min (range)	151 (41–769)		142 (45–688		0.04
Indication					0.16
Neoplasm	377	45	360	43
Diverticulitis	200	23	199	24
Inflammatory	101	12	85	10
Other	156	19	190	23
Operation extent
LAR	353	42	334	40	0.17
Right	197	24	214	26
Left	131	16	121	15
TAC	65	8	56	7
APR	61	7	65	8
Proctectomy	9	1	24	3
Stoma takedown	19	2	20	2
Processes-of-care
Epidural	155	19	104	13	<0.01
Nasogastric tube#	43	5	44	5	0.91
PCA	627	75	644	77	0.33

^*Comparison using test for the median for continuous variables that were not normally distributed. Comparison of patients who did and did not receive alvimopan using χ² tests for heterogeneity unless otherwise indicated.

^‡Calculated based on reported comorbid conditions and lab values.

^§Use of any home mobility device including walker, wheelchair, scooter, or cane.

^‖Includes laparoscopic, laparoscopic converted to open, laparoscopic/hand-assisted, robotic, and robotic converted to open

^#Nasogastric tube in place when the patient left the operating room.

PCA, patient-controlled analgesia; LAR, low anterior resection; Right, right hemicolectomy; Left, left hemicolectomy; TAC, total abdominal colectomy; APR, abdominoperineal resection.