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. 2016 Apr 28;6:24844. doi: 10.1038/srep24844

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Copyright © 2016, Macmillan Publishers Limited

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(A) Insulin tolerance test was performed 12 weeks after STZ injection. Compared to NC rats, DCP rats lacked a response to insulin (n = 6). (B) Increased collagen deposition was detected in DCP rat bladder. (C) Typical NC and DCP rat bladder cystometrogram recordings. (D–F) Effects of diabetes on cystometric parameters. The DCP bladder showed a significant decrease in MBP and increase in MV and MI (n = 30, independent-sample t-test, **P < 0.01 and ***P < 0.001).