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. 2016 Apr 28;6:25145. doi: 10.1038/srep25145

Figure 6. Effects of low protein diets on relative mRNA abundance of key regulatory molecules of thermogenesis in interscapular brown adipose tissue.

Figure 6

(a) β3-adrenergic receptors (β3-AR), (b) β2-adrenergic receptors (β2-AR), (c) peroxisome proliferator-activated receptor gamma coactivator 1 α (PGC1-α), (d) uncoupling protein 1 (UCP1), (e) fibroblast growth factor 21 (FGF21), (f) β-Klotho, (g) serotonin transporter (SERT) and (h) tryptophan hydroxylase 1 (TPH1) in obesity-prone rats. The animals were fed either a control (15% protein; 15P), moderately low protein (10% protein; 10P), very low protein (5% protein; 5P) or protein-free (0% protein; 0P) isocaloric diet for 14 days. The relative mRNA abundance was determined by qPCR using β-Actin as reference target. Values are mean ± SEM, n = 5–9. *P < 0.05 vs 15P.