. 2016 Apr 28;6:25105. doi: 10.1038/srep25105

Table 2. Stage 1 analysis showed the association of SNPs in (s)ANK1 for T2D development and the levels of HbA1c, Hb and fasting glucose.

	Gene	Effect/other	T2D Development^a	HbA1c(%)^b	HbA1c (%) adjusted for glucose, sex, age^b	Hb (g/L)^b	Hb (g/L) adjusted for sex, age^b	Fasting glucose (mmol/L)^b	Fasting glucose (mmol/L) adjusted for sex, age^b
rs4466386	ANK1	T/C	0.969 (0.789–1.191)	−0.045 (0.012)	−0.036 (0.014)	−0.10 (0.001)	−0.01 (0.002)	−0.008 (0.01)	0.002 (0.01)
			0.768	0.365	0.52	0.838	0.849	0.875	0.963
rs10090395	ANK1	C/T	1.002 (0.773–1.300)	0.054 (0.01)	0.042 (0.011)	0.038 (0.001)	0.031 (0.001)	0.027 (0.008)	0.015 (0.008)
			0.983	0.276	0.454	0.43	0.55	0.583	0.762
rs4737009	ANK1	A/G	1.034 (0.854–1.253)	−0.035 (0.013)	−0.056 (0.015)	0.051 (0.002)	0.041 (0.002)	0.018 (0.01)	0.007 (0.01)
			0.732	0.476	0.315	0.288	0.438	0.716	0.893
rs6474359	ANK1	C/T	1.010 (0.654–1.559)	−0.036 (0.007)	0.001 (0.007)	−0.61 (0.001)	−0.101 (0.001)	−0.031 (0.005)	−0.024 (0.005)
			0.963	0.464	0.987	0.213	0.054	0.528	0.623
rs508419	(s)ANK1	C/T	1.663 (1.247–2.218)	0.102 (0.009)	0.119 (0.01)	0.023 (0.001)	−0.021 (0.001)	−0.006 (0.007)	−0.018 (0.007)
			4.83 × 10⁻⁴	0.040	0.034	0.634	0.691	0.902	0.709
rs515071	(s)ANK1	C/T	1.583 (1.228–2.039)	0.104 (0.01)	0.115 (0.011)	0.049 (0.001)	0.026 (0.001)	−0.012 (0.007)	−0.026 (0.007)
			3.63 × 10⁻⁴	0.034	0.040	0.312	0.627	0.801	0.593
rs516946	(s)ANK1	C/T	1.750 (1.308–2.341)	0.106 (0.008)	0.121 (0.009)	0.032 (0.001)	−0.010 (0.001)	−0.004 (0.007)	−0.018 (0.007)
			1.41 × 10⁻⁴	0.032	0.029	0.513	0.856	0.939	0.718
rs4737000	(s)ANK1	C/A	0.972 (0.790–1.195)	0.072 (0.014)	0.085 (0.015)	−0.027 (0.002)	−0.041 (0.002)	−0.029 (0.01)	−0.039 (0.011)
			0.788	0.148	0.127	0.575	0.436	0.549	0.427

^aData were showed as OR (95% CI) (upper) and p value (lower).

^bData were showed as β (SE) (upper) and p value (lower).