Figure 4. The diverse CDR1/2 and conserved CDR3 loops in CD8αα structures.

The structural alignment shows the CDR-like loops of the six known CD8αα structures. Different colours consistent with those of the above figures were used to distinguish these six different CD8αα structures. The diverse CDR2-like loops were circled for clarity. The conserved residue N in the CDR3-like loop is shown in stick form.