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. 2016 Apr 28;6:25310. doi: 10.1038/srep25310

Figure 4. Reproducibility and sensitivity of the “EasyMF”.

Figure 4

(a) Overview of mutation frequency in pSP189 plasmid, slide window size is 100bp. X axis is the genome position, y axis is the mutation frequency of each region. (b–d) Fold changes of mutation frequency relative to corresponding siNC-UV from sub-sampled 1 Mb, 10 Mb and 50 Mb data, 3 replicates were plotted. (e) p-values of the mutation frequency difference between undamaged and UV damaged plasmids in indicated circumstances, or siPolη-UV and siNC-UV, or siREV1-UV and siNC-UV in 1 Mb, 10 Mb and 50 Mb sub-sampled data.