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. 2016 Apr 25;7:11433. doi: 10.1038/ncomms11433

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Each point represents the results from a mixed-models analysis using all SNPs with MAF>0.01 on the exome chip, adjusted for age, sex and 20 principal components. PheWAS phenotypes with P-values<10⁻¹⁶ (3 phenotypes) were set to 10⁻¹⁶ for display purposes. Phenotypes with a genetic liability estimate<0 are not shown.