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Immunostaining pattern of FOXO3 expression in breast cancers with different BRCA mutation status. (a) BRCA mutation makeup of tissue microarray constructed from 308 cases of Korean breast cancer samples. (b) Representative staining images of FOXO3 and EZH2 immunohistochemical staining of BRCA1-mutated, BRCA2-mutated or wild-type breast cancer samples. Images (original magnification, × 20); insets (original magnification, × 100).
