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. 2016 Apr 27;11:42. doi: 10.1186/s13000-016-0492-4

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© Steponaitis et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — mRNA level of CHI3L1 in different malignancy grade of astrocytic gliomas. Data expressed as log2 of fold change in CHI3L1/β-actin mRNA expression. AI–AIII - grade I-III astrocytoma’s; GBM – glioblastoma. Horizontal lines mark median, while plus indicator (+) shows mean of CHI3L1 expression in the group. Significant decrease of CHI3L1 mRNA was observed in grade II and III astrocytoma’s compared to GBM (p < 0.001) and I grade glioma (respectively p < 0.001 and p = 0.032)