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. 2016 Apr 27;11:42. doi: 10.1186/s13000-016-0492-4

Fig. 2.

Fig. 2

Methylation analysis of CHI3L1 in different grade gliomas. a Methylation frequency analyzed with first primer set while (b) with second primer set. Both primer sets detects separate CpG dinucleotides in CHI3L1 promoter CpG island. No significant association was observed among malignancy grades and CHI3L1 methylation frequency analyzed with 1-st primer set (χ2 = 3,815, df = 3, p = 0.282) and 2-nd primer set (χ2 = 1,646, df = 3, p = 0.649)